An update.
600 mg twice weekly dosing is not as effective against the arthritis, and 1200 mg dosing is in hindsight better than I thought, but neither seems as good as the twice weekly 800 mg regime that I was on. I stopped this regime because of what I believe to be a sun exposure induced lymphopaenia. Here is the data that leads me to this conclusion:
Date WBCs Neutrophils Lymphocytes
03/05/2016 4.9 3.1 1.1
22/08/2016 4.8 3.3 0.9
12/12/2016 5.4 4.1 0.6
05/01/2017 5.9 4.4 0.7
06/02/2017 5.8 4.4 0.8
06/03/2017 5.9 4.3 0.8
The sun baking commenced a little before the test on 22/08/2016 and was most frequent until 12/12/2016. I caught a cold just after the 12th and only sunbaked once before the next test. Sun baking was typically twice or three times a week, full body, and of about twenty minutes duration. The result is consistent with sun exposure increasing the total leukocyte count and DMF sensitising lymphocytes. I am now avoiding sun exposure and instead supplementing with d3. Although I could probably see my lymphocytes back above 1.0 with a month long drug holiday, the back pain is too unpleasant and I will restart 800 mg twice weekly dosing. Diet wise I have been having bread and skim milk powder. As both of these foods have triggered arthritis in the past, I will stop eating them for a while. I will also eat more salads and exercise a little more.
My feelings are mixed: It is nice to learn something and it has made me think about dosing, diet and exercise, but the episode has been painful and inconvenient.
600 mg twice weekly dosing is not as effective against the arthritis, and 1200 mg dosing is in hindsight better than I thought, but neither seems as good as the twice weekly 800 mg regime that I was on. I stopped this regime because of what I believe to be a sun exposure induced lymphopaenia. Here is the data that leads me to this conclusion:
Date WBCs Neutrophils Lymphocytes
03/05/2016 4.9 3.1 1.1
22/08/2016 4.8 3.3 0.9
12/12/2016 5.4 4.1 0.6
05/01/2017 5.9 4.4 0.7
06/02/2017 5.8 4.4 0.8
06/03/2017 5.9 4.3 0.8
The sun baking commenced a little before the test on 22/08/2016 and was most frequent until 12/12/2016. I caught a cold just after the 12th and only sunbaked once before the next test. Sun baking was typically twice or three times a week, full body, and of about twenty minutes duration. The result is consistent with sun exposure increasing the total leukocyte count and DMF sensitising lymphocytes. I am now avoiding sun exposure and instead supplementing with d3. Although I could probably see my lymphocytes back above 1.0 with a month long drug holiday, the back pain is too unpleasant and I will restart 800 mg twice weekly dosing. Diet wise I have been having bread and skim milk powder. As both of these foods have triggered arthritis in the past, I will stop eating them for a while. I will also eat more salads and exercise a little more.
My feelings are mixed: It is nice to learn something and it has made me think about dosing, diet and exercise, but the episode has been painful and inconvenient.