Increased risk of periodontitis in psoriasis patients

[Fred]

This Danish study suggests there is an increased risk of periodontitis in psoriasis patients.

Quote:

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Background:
Psoriasis and periodontitis are chronic inflammatory disorders with overlapping inflammatory pathways, but data on risk of periodontitis in psoriasis are scarce and a possible pathogenic link is poorly understood.

Objective:
We investigated the association between psoriasis and periodontitis in a nationwide cohort study.

Methods:
All Danish individuals aged ≥18 years between 1 January 1997 and 31 December 2011 (n = 5,470,428), including 54 210 and 6988 patients with mild and severe psoriasis, and 6428 with psoriatic arthritis, were linked through administrative registers. Incidence rate ratios (IRRs) were estimated by Poisson regression.

Results:
Incidence rates of periodontitis per 10 000 person-years were 3.07 (3.03–3.12), 5.89 (1.07–6.84), 8.27 (5.50–12.45) and 11.12 (7.87–15.73) for the reference population, mild psoriasis, severe psoriasis and psoriatic arthritis respectively. Adjusted IRRs were (1.66; 1.43–1.94) for mild psoriasis, (2.24; 1.46–3.44) for severe psoriasis and (3.48; 2.46–4.92) for psoriatic arthritis. Similar results were found when a case–control design was applied.

Conclusions:
We found a significant psoriasis-associated increased risk of periodontitis, which was highest in patients with severe psoriasis and psoriatic arthritis.

Source: onlinelibrary.wiley.com

*Funding: Pfizer, Leo Foundation, Novo Nordisk Foundation.

[Caroline]

Could it also be the other way around by the way ?
I mean could problems with your teeth become the trigger for psoriasis. ?

In that case the reseach has a disturbed starting point.

[Fred]

Could it also be the other way around by the way ?
I mean could problems with your teeth become the trigger for psoriasis. ?

In that case the reseach has a disturbed starting point.

Interesting thinking. I had a lot of teeth problems before getting psoriasis.

[jiml]

I had trouble with root resorption with some of my teeth in early adulthood about the same time as psoriasis was rife

[Fred]

I had trouble with root resorption with some of my teeth in early adulthood about the same time as psoriasis was rife  

Interesting. maybe we should do our own survey?

[Caroline]

I had trouble with root resorption with some of my teeth in early adulthood about the same time as psoriasis was rife  

Interesting. maybe we should do our own survey?

Could be interesting yes.
I have heard my doctor once on the issue of teeth, but I don't know anymore if that was in the same context, it might be it had to do with those old fillings in teeth.

[Bill]

Given that the immune system gets a bit haywire with uncontrolled p and psa, and given periodontal disease results from an interaction of biofilm and the immune system, a relation is not unreasonable. But it could be that all the bother simply distracts people from brushing and flossing. Truck driving is notoriously harsh on dental health.

[Fred]

Truck driving is notoriously harsh on dental health.

That's why I had problems then. But it is difficult to brush your teeth whilst driving.