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Otezla (apremilast) is an Oral prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis and psoriatic arthritis.
Dosage:
When you first start Otezla, you'll have a 5-day titration period, which means that you'll gradually increase your dose over your first 5 days until you reach the recommended dose. This titration is meant to help reduce the gastrointestinal symptoms related to initial treatment with Otezla.
Side effects:
The most common side effects of Otezla were diarrhea, nausea, and headache. These side effects occurred within the first 2 weeks of treatment and tended to go away over time without stopping Otezla.
Immune system disorders: Hypersensitivity
Investigations: Weight decrease
Gastrointestinal Disorders: Frequent bowel movement, gastroesophageal reflux disease, dyspepsia
Metabolism and Nutrition Disorders: Decreased appetite
Nervous System Disorders: Migraine
Respiratory, Thoracic, and Mediastinal Disorders: Cough
Skin and Subcutaneous Tissue Disorders: Rash
Important Safety Information:
You must not take Otezla® (apremilast) if you are allergic to apremilast or to any of the ingredients in Otezla.
Otezla is associated with an increase in adverse reactions of depression. In clinical studies, some patients reported depression and suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, suicidal thoughts, or suicidal behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.
Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.
Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.
Side effects of Otezla in psoriasis clinical studies were diarrhea, nausea, upper respiratory tract infection, tension headache, and headache.
Side effects of Otezla in psoriatic arthritis clinical studies were diarrhea, nausea, and headache.
These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.
Tell your doctor if you are pregnant, planning to become pregnant, or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.
Website: otezla.com
Dosage:
When you first start Otezla, you'll have a 5-day titration period, which means that you'll gradually increase your dose over your first 5 days until you reach the recommended dose. This titration is meant to help reduce the gastrointestinal symptoms related to initial treatment with Otezla.
Side effects:
The most common side effects of Otezla were diarrhea, nausea, and headache. These side effects occurred within the first 2 weeks of treatment and tended to go away over time without stopping Otezla.
Immune system disorders: Hypersensitivity
Investigations: Weight decrease
Gastrointestinal Disorders: Frequent bowel movement, gastroesophageal reflux disease, dyspepsia
Metabolism and Nutrition Disorders: Decreased appetite
Nervous System Disorders: Migraine
Respiratory, Thoracic, and Mediastinal Disorders: Cough
Skin and Subcutaneous Tissue Disorders: Rash
Important Safety Information:
You must not take Otezla® (apremilast) if you are allergic to apremilast or to any of the ingredients in Otezla.
Otezla is associated with an increase in adverse reactions of depression. In clinical studies, some patients reported depression and suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, suicidal thoughts, or suicidal behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla.
Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla.
Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines.
Side effects of Otezla in psoriasis clinical studies were diarrhea, nausea, upper respiratory tract infection, tension headache, and headache.
Side effects of Otezla in psoriatic arthritis clinical studies were diarrhea, nausea, and headache.
These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away.
Tell your doctor if you are pregnant, planning to become pregnant, or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding.
Website: otezla.com