Ceramics in hip replacement caused psoriasis

[Fred]

Background:
Ceramics are inorganic nonmetallic materials and are used as bioinert components in joint replacement surgeries. Ceramics are known to be low allergenic. We experienced a ceramic-induced psoriasis.

Objective:
We report a first case of possible ceramic-induced psoriasis caused by a ceramic insert.Methods:A 55-year-old female received an implanted ceramic-on-ceramic total hip replacement for osteoarthritis of the right hip joint. Following surgery, she developed psoriatic lesions, which continued for 10 years. We suspected that psoriasis was caused by a ceramic insert and removed it surgically.

Results:
When the ceramic insert was replaced with a polyethylene-on-metal hip joint, the psoriatic lesions completely disappeared.

Conclusion:
The pathogenesis of psoriasis is still an enigma, although deregulation of nuclear factor κB signaling and resulting abnormal cytokine secretion are speculated to be involved. Ceramics may affect these signaling events and cause the onset of psoriasis.

[leopardless]

Fred,

Thanks so much! I am researching PRP stem cells with a doctor Crane in St Louis, MO, instead of a hip replacment.

Had to have tonsils out before hip can be done. MD said, strep antibodies too high and I would get bone infection. Concern was gangrenous tonsils and strep making its way to bones for bone sepis. Never knew strep domiciled in tonsils and could affect heart, kidneys, brain fog, and lymph.

If i have to do a regular hip I'll certainly avoid cerarmic.

Kind regards
LL

[Caroline]

I read that this is a first case.
Is this the first case in a range of two cases? Or in a range of 1000 cases?
Certainly it is something to take serious, but we don't know yet if it is significant.

Carol

[Fred]

I read that this is a first case.
Is this the first case in a range of two cases? Or in a range of 1000 cases?
Certainly it is something to take serious, but we don't know yet if it is significant.

Carol

I read it as the first and only case as they say "suspected that psoriasis was caused by a ceramic insert. and when removed it the psoriatic lesions completely disappeared"

I think the report is suggesting ceramics may be the cause of the psoriasis, and it needs investigating.