Methotrexate - Side Effects? - Printable Version +- Psoriasis Club (https://psoriasisclub.org) +-- Forum: Health Boards (https://psoriasisclub.org/forum-1.html) +--- Forum: Prescribed Treatments For Psoriasis (https://psoriasisclub.org/forum-10.html) +--- Thread: Methotrexate - Side Effects? (/thread-6274.html) |
Methotrexate - Side Effects? - SnarkyTexan - Mon-20-05-2019 Howdy y'all, A real quick rundown of my dose of Methotrexate. Also, note that my dermatologist is a man. But I interact more with the resident under him, who is a woman. So if I get gender-confused, that's why haha My dermatologist had me start a daily regimen of folic acid 2 days before she had me start the MTX (that I skip on the days I take MTX). I was taking the MTX on Tuesday's. But because of the required labs and the clashing with my job, I had to move the dose to Wednesday. 1. I started a 2-pill dose on April 23.
3. Took the 6-pill dose on May 8.
4. Took the 2nd 6-pill dose on 14. (current dose)
Today, I'm seriously freaking tired. I went to bed last night an hour earlier than I normally do. I am considering ducking out early so I can sleep some more. I can't figure out if it's the MTX or what going on with me. It is affecting my job. I am paid by the speed I work. My pace has slowed considerably. Are my symptoms normal or am I experiencing something else? Thanks for any feedback. RE: Methotrexate - Side Effects? - Turnedlight - Mon-20-05-2019 Mtx in any dose can make you tired, I found it got worse as the dose got higher. Also though, having compromised skin is tiring for your body too, I find with a flare up if it gets past a certain coverage it feels a bit like having the flu. Hopefully you will get some results with the mtx and your dose can be reduced to a maintenance dose which you might find more able to tolerate. If it were me (here in UK) I would go back to my derm and say I can’t tolerate the drug and it’s interfering with being able to go to work, and hopefully move on to the next level of treatment. If it was starting to work and then stopped, perhaps you are already becoming resistant. It only worked for me for about a year, then it just stopped working even though the derm increased the dose. RE: Methotrexate - Side Effects? - SnarkyTexan - Mon-20-05-2019 I am scheduled to take the next dose on Wednesday. If this dose doesn't make a difference in my inverse (which is my biggest problem), then I am going to ask to move forward to the next option. This fatigue is hurting me too much to keep it up. My dr seems to be loathed to taking me off MTX until I've gone at least 2 mths of treatment. But I can't risk my job over my skin. Yes, when my inverse is particularly bad, showers are very very painful and I feel just flat out sick. I don't want to do anything or move. RE: Methotrexate - Side Effects? - Turnedlight - Mon-20-05-2019 Just in case it helps, have you tried using sudocrem out of the tub (not the tube version) it’s got a lot of zinc and I find it soothing on areas which are prone to inverse p. It’s basically a nappy (diaper) cream. RE: Methotrexate - Side Effects? - jiml - Mon-20-05-2019 Hi SnarkyTexan and welcome to the club, I'm glad you Were able to find us. You will find a lot of information about methotrexate here, some get on well with it and some hate it Foir me I tried it and used it for almost a year but I found it increasingly difficult persuading myself to take the tablets I found tiredness and lethargy a big issue plus constantly feeling unwell and nauseous. I asked to come off as I would rather have psoriasis than keep taking methotrexate I think for you it's unlikely to get easier with side effects and would be telling your dermatologist you are unhappy and should be moved on RE: Methotrexate - Side Effects? - JohnB - Mon-20-05-2019 Hi Snarky Texan, I don't think we have crossed paths yet so firstly warm welcome to our club I am currently on a break from MTX while a chest infection disappears. I did have similar muzzy head/tiredness for the first week or so but this fortunately went away. The heartburn thing though I haven't had even though I do have a hiatus hernia. Indigestion/heartburn/gastric reflux is a recognised side effect. Maybe antacids could help with this and here comes the but, many of these can have an adverse effect causing the body not to get shut of the MTX as quick as it should. I can understand the Dermys' reluctance to try something else but if you are not tolerating MTX now it will only ever get worse and I would be looking to try something else. I don't have that much experience with MTX but if you need any more advice just yell out, somebody will be happy to help JohnB RE: Methotrexate - Side Effects? - Fred - Mon-20-05-2019 It always made me feel like a zombie. I always felt tired and nauseous, and on top of that I also found I would get the odd mood swing. You do have to go through the hoops to get to a treatment that works for you, and what works for one may not work for another. It's all about starting at the bottom and working your way up, but at the end of the day ............. It's your body they are playing with and you have to decided if a treatment is for you or not. RE: Methotrexate - Side Effects? - SnarkyTexan - Mon-20-05-2019 (Mon-20-05-2019, 17:42 PM)Turnedlight Wrote: Just in case it helps, have you tried using sudocrem out of the tub (not the tube version) it’s got a lot of zinc and I find it soothing on areas which are prone to inverse p. It’s basically a nappy (diaper) cream. I have not tried that brand. My mother and I used to use Gynalotrimin. Tho it's used to treat yeast infections, it seemed to keep the inverse at bay. It's very hard to find and at some point we a gave up trying to keep up with it. My mom has suggested using deodorant, like Dove, on certain places where the skin won't stay dry. RE: Methotrexate - Side Effects? - JohnB - Mon-20-05-2019 (Mon-20-05-2019, 19:11 PM)SnarkyTexan Wrote:(Mon-20-05-2019, 17:42 PM)Turnedlight Wrote: Just in case it helps, have you tried using sudocrem out of the tub (not the tube version) it’s got a lot of zinc and I find it soothing on areas which are prone to inverse p. It’s basically a nappy (diaper) cream. When I was an awful lot younger I had a very itchy damp area on my left groin. I never got it looked at but my dad suggested cornflour (a granny remedy). It did help relieve the itch. The patch kind of disappeared but it was quite a while before I had noticed the change. RE: Methotrexate - Side Effects? - Caroline - Mon-20-05-2019 I never got so far as you are describing. When I see your description only one thing comes to my mind. Quit. This cannot be good for you. In my own situation, with quite different problems, I also have heard doctors say: “this is not caused by your Psoriasis.”, but they don’t have an explanation of what else. So for me it is clear, the Psoriasis is the cause and in your case I suspect the MTX has been causing the gallstone attack. MTX is quite some stuff, through the liver it will also reach your gall bladder, who knows what it does over there ? |