[split] from Fumaderm thread

[Bill]

No worries, Fred. And I would add that I no longer find the taste of soy milk nauseating. This is good as soy is the best milk substitute, but perplexing for me as well. I wonder whether the altered taste was a direct side effect of the drug, or a consequence of it giving me a clearer airway. If it is more a result of the latter, then that is a little worrying as it may mean that the drug is becoming less effective. I guess this is why objective measures like the PASI are so useful and potentially reassuring. I am sure I'm not the only one to find psoriasis a bit of an emotional roller-coaster.

[Caroline]

Interesting to read your progress Bill.

To me it seems you are about at the point where dr Schweckendieck was around 20 years ago.
It is clear that fumarates do the job. Your psoriasis is greatly diminishing.

But dr Schweckendieck finally had to give up because of the side effects. Hopefully you don't have to, too.
Over here in the Netherlands, dr Kunst invented a way to circumvent your problems.
I am using fumarates also, but do not have problems like you are describing. I have minimal intestine problems and an occasional flare up.
I am very interested in your progress, but know there is a solution.

Cheers,
Caroline

P.s. I am never emotional, always my cool self...........

[Bill]

Thanks, Caroline. I agree that the side effects I experienced were very unpleasant at the start of treatment and I would have welcomed some means of amelioration. But the side effects now are mild and quite bearable. Do you know what form and dosage of esters Dr Schweckendieck was taking? He may have been taking a higher dose and a combination with less efficacy and more toxicity.

It is interesting that you mention flareups as a side effect. Earlier this week, plaques on my shins, neck, and the top of my abdomen became a shade redder quite quickly. They have since faded. Is that what you meant by flareups?

[Caroline]

(Fri-25-01-2013 11:14 AM)Bill Wrote:  Thanks, Caroline. I agree that the side effects I experienced were very unpleasant at the start of treatment and I would have welcomed some means of amelioration. But the side effects now are mild and quite bearable. Do you know what form and dosage of esters Dr Schweckendieck was taking? He may have been taking a higher dose and a combination with less efficacy and more toxicity.

Hi Bill,
No I don't know exactly how dr Schweckendieck treated himself (and his wife), I guess it somewhere can be found. I could make a try on finding out, but that may take some time as I may have to ask for at some people.

(Fri-25-01-2013 11:14 AM)Bill Wrote:  It is interesting that you mention flareups as a side effect. Earlier this week, plaques on my shins, neck, and the top of my abdomen became a shade redder quite quickly. They have since faded. Is that what you meant by flareups?

No, that is not what I mean by a flareup, maybe I should name it differently. You can also call it a flush.
The effect is because of the DMF and it cannot be predicted. It starts at the top of my head, which begins to tickle en if thousands of little needles are stuck into it. But it is not painful. By then I gradually, from my head first, turn completely red. I think it has to do with the extents of the blood vains. It takes between 20-30 minutes for me to become completely red (and warm) and to cool down again and get my normal color.
Sometimes it stops earlier and it will only be on my head. This occurs occasionally, on average about one time a week. Luckily mostly in the nights, so I sleep through it.